Table 1. List of the genes used for the PAM50 classification
SymbolHistologyBC vs. LPBC vs. LCLC vs. LP
ACTR3B
ANLN
BAG1
BCL2DNUP
BIRC5
BLVRAUP
CCNB1
CCNE1
CDC20
CDC6
CDH3
CENPF
CEP55
CXXC5UP
EGFRUPDN
ERBB2
ESR1 DNDN
EXO1
FGFR4
FOXA1DNUP
FOXC1DN
GPR160DNUP
GRB7
KIF2C
KRT14UPUP
KRT17UPUP
KRT5UPUPDN
MAPT
MDM2
MELK
MIADNDN
MKI67
MLPHDNDNUP
MMP11
MYBL2
MYC
NAT1DNUP
NDC80
NUF2
ORC6
PGRUP
PHGDHDN
PTTG1UP
RRM2
SFRP1UPDN
SLC39A6UP
TMEM45BDNUP
TYMS
UBE2C
UBE2T
  • Gene products used routinely in histological studies (✓) and transcripts increased (UP) or decreased (DN) in mammary epithelial cells are marked. Differential gene expression data are based on the RNA‐seq data presented in Pellacani et al (2016).