Table 2. Topological comparison of the CCP modules in β2GPI, CD46, VCP and FcH
    β2GPI CCP1β2GPI CCP2β2GPI CCP3β2GPI CCP4
β2GPICCP21.82 (15) [43]
CCP31.49 (10) [50]1.49 (16) [50]
CCP41.54 (10) [42]1.74 (2) [23]1.20 (19) [55]
CD46CCP11.45 (15) [46]1.48 (4) [23]1.42 (6) [43]1.54 (4) [39]
CCP22.24 (4) [25]1.22 (0) [13]1.76 (10) [45]1.38 (0) [6]
VCPCCP31.39 (8) [24]1.85 (8) [32]1.53 (7) [41]1.71 (2) [20]
CCP41.93 (12) [44]1.44 (17) [44]1.61 (1) [20]1.18 (16) [43]
FcHCCP152.09 (11) [43]1.28 (8) [29]1.92 (9) [49]1.65 (6) [28]
CCP161.70 (11) [29]NFAa1.65 (6) [46]NFA
  • a No feasible alignment.

  • For each comparison, the first number indicates the r.m.s.d (Å) between equivalent Cα residues. The middle (in parentheses) and last (in brackets) numbers indicate the number of identical and matching residues, respectively, as calculated with the program TOP (Lu, 1996).