Table 4. Calcium‐dependent facilitation of CaV1.2 variants
CaV1.2nCDF (%)P
I1624A3171.2±22.5N/A
A‐regionL1562A/F1563A/I1624A638.4±12.4**
Dimer interfaceL1585A/I1588A/I1624A1466.9±25.5NS
C‐regionW1593A/I1624A1450.3±13.3**
W1593E/I1624A1254.4±13.2*
Dimer interface/C‐regionL1585A/I1588A/W1593A/I1624A1438.2±12.9***
L1585A/I1588A/W1593E/I1624A149.6±3.8***
  • NS, not significant.

  • CDF was calculated by (Imax_40Imax_1)/Imax_1 × 100 and displayed as mean±s.d values. P‐values with respect to I1624A are shown and were calculated using Student's t‐test; NS, P>0.05; *, 0.01<P<0.05; **, 0.001<P<0.01; ***, P<0.001. Error bars indicate s.d.