Table 2. Incidence of histological abnormalities in E18.5 embryos expressing the soluble FGFR2 mutant
OrganNo. of embryos examinedDysgenesisaAgenesisa
Lung88
Thyroid55
Anterior pituitary33
Tooth buds66
Salivary glands55
Kidney835
Hair follicles844
Inner ear88
Thymus88
Glandular stomach88
Pancreas88
aDysgenesis is defined as malformation or reduction in number or size, and agenesis as absence of organ. See text for details.