Table 1. Properties of some common detergents in the run‐down assay
Detergentc.m.c. (mM)Concentration for 5% inhibition (mM)Concentration for total inhibition (mM)Concentration for total lysis (mM)
Cholate9–150.010.110
Cholate (purified)a9–150.030.5>10
Lubrol‐PX0.10.010.10.3
Octyl‐β‐glucoside20–250.0610>10
Triton X‐1000.2–0.90.0020.10.3
Genapol C‐1000.0020.030.3
CHAPS6–100.33>10
  • The c.m.c. values are as reported by the suppliers at 50 mM Na. The experimental concentrations referred to in the table are taken from dose–response curves of the respective detergent at 5 min run‐down in the assay as described in the text.

  • a Sternweis and Pang (1990).