Table 1. Characteristics of the leukemias in recipients of MLL‐CBP‐transduced BM cells
MouseLatency (days)WBC (103/μl)Percentage monocyteaRBC (106/μl)PLT (103/μl)Spleen weight (g)
MIEMLL–CBP# 6126NDNDNDND0.85
MIEMLL–CBP# 4129NDNDNDND0.36
MIEMLL–CBP# 11596.3141118700.65
MIEMLL–CBP# 1015941432.72500.32
MIEMLL–CBP# 51655365.53690.53
MIEMLL–CBP# 81721211.34580.43
MIEMLL–CBP# 9172120402.52480.70
MIEMLL–CBP# 3178NDNDNDNDND
MIEMLL–CBP# 218866245.36580.53
MIEMLL–CBP# 71887244.44690.36
MIEMLL–CBP miceb164 ± 744 ± 1422 ± 54.7 ± 1342 ± 930.46 ± 0.05
MIE miceaNA8 ± 0.97 ± 110 ± 0.31050 ± 950.090 ± 0.01c
  • ND, not determined; NA, not applicable.

  • a Differential counts determined by the Cell‐Dyn counter.

  • b Values shown are the mean (± standard error of the mean) from the 10 MIEMLL–CBP mice at the time of sacrifice, or the 10 control MIE mice bled 158 days after reconstitution.

  • c Spleen weight from age‐matched mice.