Table 1. PcG proteins and histone modifications recruited by Xist
EedEzh2Suz12Ring1bMph1Mph2*H3K27me3H4K20me1H2AK119ub1
3689±3%79±9%88±3%56±7%48±11%33±8%96±1%82±13%97±2%
n=624n=346n=629n=368n=502n=470n=346n=410n=488
36Eed−/−0013±2%NDNDND050±10%98±0%
Clone1n=510n>600n=624n>600n=227n=479
36Eed−/−007±1%53±8%00036±7%ND
Clone2n=634n>600n=629n=478n=650n=456n>600n=224
  • The percentage of focal signals colocalising with Xist RNA in ES cells treated with doxycycline for 3 days, or after 8 days of differentiation in the presence of doxycycline (*). Mean±s.d. of three independent slides and the total number of nuclei counted (n) are indicated.