aPKC‐mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

Christian A Smith, Kimberly M Lau, Zohra Rahmani, Sascha E Dho, Greg Brothers, Ye Min She, Donna M Berry, Eric Bonneil, Pierre Thibault, François Schweisguth, Roland Le Borgne, C Jane McGlade

Author Affiliations

  1. Christian A Smith1,2,,
  2. Kimberly M Lau1,2,,
  3. Zohra Rahmani3,
  4. Sascha E Dho2,
  5. Greg Brothers4,
  6. Ye Min She4,
  7. Donna M Berry2,
  8. Eric Bonneil5,
  9. Pierre Thibault5,
  10. François Schweisguth3,
  11. Roland Le Borgne3, and
  12. C Jane McGlade*,1,2
  1. 1 Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
  2. 2 Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
  3. 3 Ecole Normale Supérieure. CNRS UMR 8542, Paris Cedex, France
  4. 4 Advanced Protein Technology Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
  5. 5 Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, Quebec, Canada
  1. *Corresponding author. Program in Cell Biology, Hospital for Sick Children, 555 University Ave, Toronto, ON, Canada, M5G 1X8. Tel.: +416 813 8657; Fax: +416 813 8456; E‐mail: jmcglade{at}
  1. These authors contributed equally to this work

  • Present address: CNRS UMR 6061; Université de Rennes I, 2 avenue du Pr. L. Bernard, CS 34317, 35043 Rennes Cedex, France

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