BAG‐1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

David Bimston, Jaewhan Song, David Winchester, Shinichi Takayama, John C. Reed, Richard I. Morimoto

Author Affiliations

  1. David Bimston1,
  2. Jaewhan Song1,
  3. David Winchester2,
  4. Shinichi Takayama3,
  5. John C. Reed3 and
  6. Richard I. Morimoto*,1
  1. 1 Department of Biochemistry, Molecular Biology and Cell Biology, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL, 60208, USA
  2. 2 Department of Surgery, Evanston Hospital, Northwestern University School of Medicine, La Jolla, CA, 92037, USA
  3. 3 The Burnham Institute, La Jolla, CA, 92037, USA
  1. *Corresponding author. E-mail: r-morimoto{at}
  1. D.Bimston and J.Song contributed equally to this work

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